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NVIDIA has completed a 104-qubit fault-tolerant quantum computing simulation on the JUPITER supercomputer at the Jülich Supercomputing Center in Germany, calling it the largest complete simulation of a fault-tolerant quantum processor to date. The simulation validated the magic state cultivation method, requiring 90% fewer physical qubits than previous methods, and ran under real noise conditions. The research team first developed the method on the GB200 NVL72 system at NVAQC, then scaled it to 8,192 GPUs on JUPITER, using cuQuantum and CUDA-Q to complete the computation.
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#Safety / alignment#Agents#DeepSeek
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A Mass General Brigham team developed two tools, FAHR-FaceAge and FAHR-FaceSurvival, which can estimate biological age from a single facial photo and directly predict survival outcomes in cancer patients. The study was published in Lancet Digital Health, and the model was trained on more than 40 million facial photos of people of different ethnicities and ages. Among cancer patients receiving radiotherapy in the United States, those who looked 5 years or more older than their actual age had a 21% higher risk of death over an average four-year follow-up period, while those who looked 5 years or more younger had a 17% lower risk. The researchers said this is the first demonstration that an AI model can directly predict cancer survival from a photo, but stressed that more research is needed before widespread use.
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The Anthropic Institute released "The AI Expectations Gap" on October 16, 2026. The survey shows that Anthropic employees on average expect that by 2030 AI will be able to complete tasks corresponding to 75% of their current working hours, while the average expectation among employed Americans is only 28%. The two groups broadly agree in their judgments of AI's current capabilities; the divergence is concentrated in the pace of technological progress and the scope of enterprise adoption in the coming years. For example, 90% of employees expect that by 2027 AI will be capable of designing and publishing research tasks, while only 38% of the public expects so. Despite expecting a high degree of task automation, 95% of Anthropic employees still believe the company's total headcount will increase over the next 12 months, with a median expected growth of 66%.
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An international team comprising institutions such as the University of Washington, the University of Oxford, and NVIDIA published the RFdiffusion3 design scheme in Science; the system can model individual atoms and is used to design proteins and nucleic acids. RFdiffusion3 references the AlphaFold3 network architecture, representing a single amino acid with up to 14 atoms and directly adjusting the three-dimensional coordinates of each atom. In comparative tests on 41 existing enzyme active sites, it outperformed RFdiffusion2 in 37 cases, with a generation speed about ten times faster; the paraoxon-degrading enzyme and peptide-cleaving enzyme it designed completed the expected chemical reactions in real experiments. The team open-sourced RFdiffusion3 on December 3, 2025.
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Morgan Stanley strategists Nick Lentini, Mike Wilson and others released the report "Tracking the $1.6 Trillion AI Money Flow," which for the first time traces hyperscalers' $1.58 trillion in 2027 capital expenditure line by line to specific companies' revenue. The report says AI capital expenditure will drive about 25% of S&P 500 sales growth, of which about two-thirds, or roughly $690 billion, flows to Nvidia, while the other 499 constituents together account for about $339 billion. The report also notes that hyperscalers have disclosed more than $1.1 trillion in lease commitments not yet commenced, which are economically equivalent to debt financing, and projects that 2027 will be the year with the largest free cash flow gap for them.
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Anthropic’s junior share of technical headcount slid from 21% to 14% while the company tripled in size, and about a third of Anthropic’s ML managers and a fifth of its SWE managers said AI has them hiring less. During the same time its agents logged 6x human hours. https://t.co/jBpoeyPvv8
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Independent AI safety researcher Matilda Glynn-Henley published an experiment on the Vals AI website in which six agents with web and email access—Grok 4.7, Claude Fable 5.1, Gemini 3.8 Flash, GPT-6 Astra, Muse Spark 1.3, and Claude Opus 5.5—sought a refund for a canceled £350 train ticket. Grok 4.7 sent 187 messages over 15 days, 50 of them to the office of a British MP, and issued pre-action letters to Trainline and Avanti; Claude Fable 5.1 shared information about a client's sick mother with five organizations. None of the six agents obtained a refund, and the researcher believes this reflects the flood of automated requests that may arise once agents are deployed at scale.
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Researchers from Microsoft and City University of Hong Kong propose Taste-Bench, using 502 binary-choice questions to evaluate AI agents' ability to make long-term decisions in long-horizon tasks. The best-performing model, GPT-5.6 Sol, achieves only 59.7% average accuracy, while GPT-5.5 reaches 59.5%. When key clues only become apparent after substantial subsequent work, the average accuracy of all models drops to 21%, close to random guessing, and increasing the reasoning budget brings almost no improvement. The researchers also distilled the teacher model's judgments using Qwen3.6-27B as the base model; the student's accuracy on unseen tasks rose from 30% to 47.9%, and its success rate on 41 SWE-bench Pro tasks increased from 14.6% to 33.7%.
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